Design and development of MEMS biosensors

Mahmoodi, Nasim (2017). Design and development of MEMS biosensors. University of Birmingham. Ph.D.

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This thesis is focused on design and development of two types of MEMS bio/chemical sensors and the deposition of a thin Au film for functionalization of the sensors with thiol-SAMs.

The effect of Au deposition rate on the morphology and crystallinity of the deposited Au film by thermal evaporation at room temperature on silicon was investigated. Formation of homogenous thiol-SAMs has been shown on the manufactured Au coated samples.

A micro-paddle resonator as a potential mass sensor in a gas environment has been proposed. FIB machining was used to fabricate the prototype device on 500 nm thick LPCVD silicon nitride. The dynamic response of the sensor was investigated over a range of pressure and compared with the simulation results. The sensitivity of the sensor was determined experimentally to be 1.61 fg/Hz. The application of the sensor for detection of Au nanoparticles was shown.

A novel type of hybrid static-dynamic micro sensor for detection in an aqueous medium was studied. This sensor is comprised of a thin membrane and a double-ended-tuning-fork (DETF) structure. The sensitivity of the sensor was numerically determined to be 91 Hz/(mJ/m2). FIB is used to make a high resolution Al2O¬3 mask for fabrication of the DETF structure.

Type of Work: Thesis (Doctorates > Ph.D.)
Award Type: Doctorates > Ph.D.
College/Faculty: Colleges (2008 onwards) > College of Engineering & Physical Sciences
School or Department: School of Engineering, Department of Mechanical Engineering
Funders: None/not applicable
Subjects: Q Science > QH Natural history > QH301 Biology
T Technology > TJ Mechanical engineering and machinery


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