Waite, Jane (2012)
Ph.D. thesis, University of Birmingham.
Restricted to Repository staff only until 01 April 2017.
In a series of studies, repetitive behaviour, executive function development and the links between these constructs were explored in Rubinstein-Taybi syndrome (RTS). An overview of these constructs provided evidence that executive dysfunction might underpin repetitive behaviour and justified the use of a developmental trajectory approach. Repetitive behaviour was explored in RTS in relation to Autism Spectrum Disorder (ASD), Down and Fragile-X syndromes. Body stereotypy and repetitive questioning occurred at a similar frequency in RTS and ASD, but repetitive phrases occurred less frequently in RTS. A test battery was compiled and administered to profile the developmental trajectories of executive functions in
RTS relative to typically developing children. Executive function development was delayed in RTS relative to mental age. Finally, the relationships between executive function
development and repetitive behaviour were explored in RTS using correlational analyses. Repetitive questioning was related to poorer scores on verbal working memory and inhibition measures. Adherence to routines was related to poorer scores on a measure of shifting and emotional regulation, and completing behaviour was related to poorer scores on shifting measures. These findings highlight the merit of studying executive function development in disorder groups and that pathways can be mapped between cognition and behaviour. The implications of these findings for research and practice are discussed.
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