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A study investigating the mechanical testing of a novel dental restorative material and its biocompatibility

Awan, Mumtaz (2010)
M.Phil. thesis, University of Birmingham.

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Dental composite materials are evolving continuously with novel Resin Based Composites being at the forefront of dental restorations. The characteristics of these materials need to be such that they are able to withstand both mechanical (masticatory) stress and any chemical activity. The current study investigates the strength and biocompatibility of three Resin Based Composites (RBCs); Ormocer Admira (VOCO, Cuxhaven, Germany), dimethacrylate FiltekTMZ250 (St Paul, MN, US) and a novel RBC namely X-tra Fil (VOCO, Cuxhaven, Germany). These materials were tested using bi-axial flexure, vickers hardness, water sorption and water solubility tests, but a one-way ANOVA showed no significant difference between their mechanical properties. Cytotoxicity tests were also performed by culturing RBC specimen discs both directly and indirectly with ATCC mouse 3T3 fibroblasts and undifferentiated pulpal fibroblast cells (OD21 cells). These determined that all three materials were cytotoxic to both the cell types, however a one-way ANOVA test showed that there was no significant difference between the materials. This suggests that all the materials exerted a similar cytotoxic effect. Therefore, the current study indicated that the mechanical and cytotoxic properties of X-tra fil are not an improvement but are similar to those materials already available on the market. However, this study provides a good origin for further research into the properties of these materials.

Type of Work:M.Phil. thesis.
Supervisor(s):Fleming, G J P and Cooper, P R and Sloan, A J
School/Faculty:Colleges (2008 onwards) > College of Medical & Dental Sciences
Department:School of Dentistry
Institution:University of Birmingham
ID Code:1309
This unpublished thesis/dissertation is copyright of the author and/or third parties. The intellectual property rights of the author or third parties in respect of this work are as defined by The Copyright Designs and Patents Act 1988 or as modified by any successor legislation. Any use made of information contained in this thesis/dissertation must be in accordance with that legislation and must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the permission of the copyright holder.
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