Stow, Ruth Elizabeth (2015). A cluster randomised feasibility trial evaluating six-month nutritional interventions in the treatment of malnutrition in care homedwelling adults. University of Birmingham. M.Res.
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Stow15MRes_Redacted.pdf
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Abstract
Evidence for nutritional interventions to address protein-energy malnutrition in the care home setting is lacking. To define outcomes and optimise the design for an adequately powered randomised controlled trial to compare the efficacy of established nutrition support interventions, a cluster randomised feasibility trial was undertaken. Ninety-three care home residents at risk of malnutrition were identified across six UK care home sites. Homes were cluster randomised to receive food-based intervention, oral nutritional supplement intervention, or standard care, for six months. Key outcomes were trial feasibility and acceptability of design, allocated interventions and outcome assessments. The trial design was feasible to undertake. Recruitment and retention targets for care homes and residents were met and the interventions were acceptable to residents and staff. Weight, body mass index (BMI) and mid-arm circumference were feasible and acceptable measurements to undertake, but measurement of function and patient-centred outcomes was hampered by dementia and immobility. A definitive trial comparing the efficacy of nutrition support interventions in increasing weight and BMI in malnourished care home residents can be conducted. However, this feasibility trial has highlighted a current lack of clinically relevant outcome measures, which are feasible to undertake in this setting.
Type of Work: | Thesis (Masters by Research > M.Res.) | |||||||||
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Award Type: | Masters by Research > M.Res. | |||||||||
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College/Faculty: | Colleges (2008 onwards) > College of Life & Environmental Sciences | |||||||||
School or Department: | School of Sport, Exercise and Rehabilitation Sciences | |||||||||
Funders: | None/not applicable | |||||||||
Subjects: | H Social Sciences > HD Industries. Land use. Labor > HD28 Management. Industrial Management Q Science > QP Physiology R Medicine > RA Public aspects of medicine R Medicine > RC Internal medicine |
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URI: | http://etheses.bham.ac.uk/id/eprint/5984 |
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