Development of micro-structured surfaces with superhydrophobic/superamphiphobic properties for anti-biofouling applications

Jitniyom, Thanaphun ORCID: 0000-0003-0688-4268 (2025). Development of micro-structured surfaces with superhydrophobic/superamphiphobic properties for anti-biofouling applications. University of Birmingham. Ph.D.

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Abstract

Droplet-based wetting phenomena are integral to the design and functionality of biomedical engineering devices, playing a critical role in applications such as drug delivery, diagnostics, tissue engineering, and medical implants. This research investigates these phenomena in the context of developing advanced biomedical devices, focusing on fabricating various surface structures, including nano-microstructures and doubly re-entrant designs, using techniques such as laser abrasion and high-performance 3D printing. The study explores how surface topography, chemistry, and roughness modulate droplet behavior, with particular emphasis on droplet adhesion, spreading, and motion. In addition, this research explores the interactions between liquid droplets and surface structures, with a focus on hydrophobic, superhydrophobic, and superamphiphobic properties. Furthermore, chemical treatments are applied to assess their effects on surface energy and lubricant infusion, while surface roughness is characterized to evaluate its impact on bacterial resistance and lubricant retention. The investigation also examines droplet repellency through measurements of contact angles and contact angle hysteresis, complemented by high-speed imaging to capture the dynamic behavior of droplets on structured surfaces. In addition, the functionality of lubricant-infused surfaces and superhydrophobic properties are assessed through bacterial adhesion tests, with antimicrobial efficacy evaluated using confocal microscopy and image analysis. The study further probes the anti-biofouling properties of Zinc Oxide nanoparticles (ZnO-NPs) coated surfaces against Escherichia coli (E.coli) and Staphylococcus aureus (S.aureus), investigating bacterial viability and cell membrane integrity through advanced microscopy techniques. Ultimately, this comprehensive research aims to advance the development and high-performance biomedical devices by integrating the fundamental principles of droplet wetting and surface engineering with practical healthcare applications.

Type of Work:

Thesis (Doctorates > Ph.D.)

Award Type:

Doctorates > Ph.D.

Supervisor(s):