A critical analysis of the ‘science play’ The Nature of Things examining the dramaturgical challenges of integrating biography, science and art. The overall aim was to create an original, imaginative and coherent theatrical experience for a general audience to access compelling human stories, exquisite phenomena and life-changing ideas that would otherwise be limited to the select few.  The play tells the story of ‘Dorothy Hodgkin and Crystallography’ interpreted using drama, dance and design/digital media. Crystallography is a powerful technique used to determine the structure of molecules such as insulin and DNA. Other significant characters include Kathleen Lonsdale, Rosalind Franklin, William Bragg, John Desmond Bernal (Sage), as well as Crick, Watson and Wilkins.  The work was crafted to expose a profound emotional connection between the supposedly opposing cultures of science and art.