Breast cancer in the West Midlands: an evaluation of screening, treatment and survival

207 23 551 8 785 document 551 Teale97PhD.pdf application/pdf c14c92bf766f1241550080a632d4257b MD5 8716968 2011-07-19 16:14:12 http://etheses.bham.ac.uk//id/eprint/207/1/Teale97PhD.pdf 207 1 1 application/pdf application/pdf en public

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http://eprints.org/relation/isVersionOf http://etheses.bham.ac.uk/id/document/551 http://eprints.org/relation/isVolatileVersionOf http://etheses.bham.ac.uk/id/document/551 http://eprints.org/relation/isIndexCodesVersionOf http://etheses.bham.ac.uk/id/document/551 archive 4031 disk0/00/00/02/07 2009-01-23 15:56:02 2019-01-23 09:51:43 2011-07-19 16:14:12 thesis show 0 Teale Alison Mary Jennifer Lawrence Gill Winter Heather Griffiths R. K. (Rod K.) University of Birmingham Breast cancer in the West Midlands: an evaluation of screening, treatment and survival unpub R1 RA0421 40fac_med Scanned from the typescript. The optical character recognition process has rendered some characters in inconsistent fonts or styles. New title page added to reflect author's change of name High quality population based data are essential to evaluate breast cancer. This study has improved data quality at the West Midlands Cancer Intelligence Unit through the development of a staging algorithm which significantly increased the proportion of cases with stage recorded. It has also demonstrated the benefits of combining cancer registry data with those from the NHS Breast Screening Programme (NHSBSP). This study identified stage as the most significant prognostic factor for breast cancer patients, and the favourable staging characteristics of screen detected cancers thus suggest that improved survival should result. The study also found that only 31.6% of cancers in eligible women were screen detected in the prevalent round. As 31% of breast cancers arose in women in the screening age range, only an estimated 10% of breast cancer patients benefit directly from screening. High interval cancer rates were identified, along with the need for clarification of the definitions used to identify interval cancers. This investigation identified changes in treatment over time across the region towards the King's Fund guidelines. However, treatment varied across the region and clear divergences from the guidelines were apparent. Furthermore, no association was identified between surgical caseload and survival, suggesting that the use of caseload as a proxy for specialist care may be questionable. 1997-12-11 graduation 1386909 eng author unchecked This unpublished thesis/dissertation is copyright of the author and/or third parties. The intellectual property rights of the author or third parties in respect of this work are as defined by The Copyright Designs and Patents Act 1988 or as modified by any successor legislation. Any use made of information contained in this thesis/dissertation must be in accordance with that legislation and must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the permission of the copyright holder. public 282 University of Birmingham Public Health and Epidemiology d_ph FALSE na 1997-12-11 graduation