Executive and attentional function in adults with Tourette syndrome with and without co-morbid obsessive compulsive disorder

Formby, Caroline (2003). Executive and attentional function in adults with Tourette syndrome with and without co-morbid obsessive compulsive disorder. University of Birmingham. Clin.Psy.D.

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The objective of this study was to investigate performance on ‘everyday’ executive and attention function tasks in adults with Tourette Syndrome (TS). Three main hypotheses were tested. The first was that adults with TS would perform more poorly than a matched group of participants without TS on tests of executive and attention function. Secondly, TS participants with co-morbid OCD would perform more poorly on the same measures than TS participants without OCD. Thirdly, that tic severity would be predictive of OCD severity and performance on the same executive and attention tasks. Results revealed significant differences between the TS and non-TS groups on two subtests measuring planning, organisational and self-monitoring ability and auditory-verbal working memory as well as on a self-report measure of behaviours associated with executive function. No further significant differences were observed between groups. There were no differences found on performance of executive function between the TS with OCD and TS without OCD groups. Regression analysis indicated that a subtest measuring mental flexibility and response suppression was a significant predictor of tic severity. Results were discussed with relation to different basal ganglia-thalamo-cortical pathways and with relation to issues of ‘ecological validity’ and assessment of executive function. Overall, results were interpreted with caution due to the relatively small sample size and the nature of the assessment measures employed.

Type of Work: Thesis (Doctorates > Clin.Psy.D.)
Award Type: Doctorates > Clin.Psy.D.
Licence: All rights reserved
College/Faculty: Schools (1998 to 2008) > School of Psychology
School or Department: School of Psychology
Funders: None/not applicable
Subjects: B Philosophy. Psychology. Religion > BF Psychology
URI: http://etheses.bham.ac.uk/id/eprint/13832


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