Outcomes of implant based prosthetic oral rehabilitation of head and neck oncology patients

Laverty, Dominic Peter ORCID: 0000-0003-0913-3339 (2020). Outcomes of implant based prosthetic oral rehabilitation of head and neck oncology patients. University of Birmingham. M.Sc.

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Aims: To conduct a systematic review on dental implant survival in autogenous bone grafts and flaps in head and neck (H&N) oncology patients.
Thereafter, to retrospectively report a service evaluation on implant- and prosthetic-outcomes of implant based oral rehabilitation in H&N oncology patients in a regional centre.

Method: For the systematic review, various databases were searched (01/1980-08/2017).
Retrospective analysis of implant- and prosthetic- outcomes of 167 patients treated within service from 2012-2017 was also undertaken, applying Kaplan-Meier survival curves and Cox proportional-hazards models.

Results: For the systematic review, 20 articles were reviewed, reporting on 1905 implants. Implant survival varied from 54-100%.
The service evaluation revealed implant survival estimates of 95.7% [95%CI 94.3-97.2%] at 3-years and 95.5% [95%CI 93.9-97.0%] at 5-years. Higher implant failure rates were shown in autogenous bone grafts/flaps in comparison to native bone (p=<0.001).
Fixed implant prostheses had a higher 5-year survival and 5-year complication-free survival, with fewer complications compared to removable implant prostheses.

Conclusion: The systematic review revealed implant survival in autogenous bone grafts in H&N oncology patients to be promising. The service evaluation supported the use of dental implants in the rehabilitation of H&N cancer patients, whilst demonstrating the risk of prosthetic failure and complications.

Type of Work: Thesis (Masters by Research > M.Sc.)
Award Type: Masters by Research > M.Sc.
Addison, OwenUNSPECIFIEDorcid.org/0000-0002-0981-687X
Chapple, Iain LUNSPECIFIEDorcid.org/0000-0003-2697-7082
Licence: All rights reserved
College/Faculty: Colleges (2008 onwards) > College of Medical & Dental Sciences
School or Department: School of Dentistry
Funders: None/not applicable
Subjects: R Medicine > RK Dentistry
URI: http://etheses.bham.ac.uk/id/eprint/10539


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