Real time cell metabolism by NMR

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Roberts, Jennie ORCID: https://orcid.org/0000-0001-7372-8498 (2020). Real time cell metabolism by NMR. University of Birmingham. Ph.D.

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Abstract

Metabolism is now widely recognised as an important hallmark of disease. Measuring metabolism is therefore an important endeavour to identify and elucidate disease states.

NMR is used for the study of live samples, from cells to whole organisms, due to its non-invasive, non-destructive nature. A variety of different approaches have been proposed for real-time analysis of live samples including bioreactors that perfuse nutrients to sustain cells during acquisition. The purpose of this thesis is to further develop real-time applications for NMR studies of mammalian cell metabolism using an NMR flow system.

Type of Work: Thesis (Doctorates > Ph.D.)
Award Type: Doctorates > Ph.D.
Supervisor(s):
Supervisor(s)EmailORCID
Gunther, Ulrichu.l.gunther@bham.ac.ukUNSPECIFIED
Bonifer, Constanzec.bonifer@bham.ac.ukUNSPECIFIED
Licence: All rights reserved All rights reserved
College/Faculty: Colleges (2008 onwards) > College of Medical & Dental Sciences
School or Department: Institute of Cancer and Genomic Sciences
Funders: Biotechnology and Biological Sciences Research Council
Subjects: Q Science > QP Physiology
URI: http://etheses.bham.ac.uk/id/eprint/10394

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