Dutton, Mark Jason (2016). Synthesis and application of stereogenic nitrogen-containing ammonium salts as phase-transfer catalysts. University of Birmingham. Ph.D.
|
Dutton16PhD.pdf
PDF - Accepted Version Download (6MB) |
Abstract
The chirality of nitrogen was at the forefront of chemistry over 110 years ago. Since then it has been widely under-acknowledged as a potential chirality source in organic synthesis. This thesis demonstrates the diastereoselective formation of stereogenic nitrogen-containing ammonium salts. Over 150 compounds were synthesised and employed as phase-transfer catalysts in order to assess the chiral-at-nitrogen influence on the outcome of two common phase-transfer-catalysed reactions. Several X-ray crystal structures of single diastereoisomer chiral-at-nitrogen ammonium salts were isolated as well as the synthesis of a library of secondary and tertiary amines.
| Type of Work: | Thesis (Doctorates > Ph.D.) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Award Type: | Doctorates > Ph.D. | |||||||||
| Supervisor(s): |
|
|||||||||
| Licence: | ||||||||||
| College/Faculty: | Colleges (2008 onwards) > College of Engineering & Physical Sciences | |||||||||
| School or Department: | School of Chemistry | |||||||||
| Funders: | None/not applicable | |||||||||
| Subjects: | Q Science > Q Science (General) Q Science > QD Chemistry |
|||||||||
| URI: | http://etheses.bham.ac.uk/id/eprint/6755 |
Actions
 |
Request a Correction |
 |
View Item |
Downloads
Downloads per month over past year