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Physical properties of particles and their implications for the calculation of the human regional lung dose

Vu, Van Tuan (2016)
Ph.D. thesis, University of Birmingham.

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This study aims to investigate the physical properties of particles and their implications for source apportionment and health human exposure studies. A wide range of particle number size distribution (PNSD) measurements was conducted in selected environments using state-of-the-art high time resolution instruments. It is found that PNSD varied in different environments, depending on emission sources and atmospheric processes. A mass balance model was used to predict the penetration, infiltration factors, deposition and loss rates of indoor particles. The loss rates of indoor particles, which are mainly subject to deposition, coagulation and evaporation, were found to be a function of particle size and time. Moreover, HTDMA measurements were performed to study the hygroscopic properties of particles in outdoor and indoor environments, and from five major indoor sources. The particles emitted from indoor sources were mostly hydrophobic. An enhanced lung deposition model based on the ICRP and MPPD models was developed to predict the deposition fraction of particles in the human respiratory tract, with consideration of their hygroscopicity. Furthermore, a combination of lung deposition models and the PMF technique was applied to identify which sources are mostly responsible for deposited particles in the different regions of lung.

Type of Work:Ph.D. thesis.
Supervisor(s):Harrison, Roy and Delgado-Saborit, Juana Maria
School/Faculty:Colleges (2008 onwards) > College of Life & Environmental Sciences
Department:School of Geography, Earth and Environmental Sciences
Subjects:RA0421 Public health. Hygiene. Preventive Medicine
RC Internal medicine
TD Environmental technology. Sanitary engineering
Institution:University of Birmingham
ID Code:6911
This unpublished thesis/dissertation is copyright of the author and/or third parties. The intellectual property rights of the author or third parties in respect of this work are as defined by The Copyright Designs and Patents Act 1988 or as modified by any successor legislation. Any use made of information contained in this thesis/dissertation must be in accordance with that legislation and must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the permission of the copyright holder.
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