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The association between sleep and obesity and its impact on health and wellbeing

Hosseini Araghi, Marzieh (2014)
Ph.D. thesis, University of Birmingham.

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The focus of this thesis was to investigate, especially in the context of obesity, the interactions among sleep duration and quality, and adverse health outcomes. Three comprehensive studies are described in the thesis:
1. A cross-sectional epidemiological study examined factors that are associated with both short and long sleep duration among an older Chinese population, and also assessed whether there was a link between sleep duration and chronic conditions such as obesity, hypertension, and diabetes. This study showed that long sleep duration was associated with increased risk for obesity among women. Additionally, demographic, socio-economic, and medical conditions were associated with sleep duration. Identifying potential factors that affect sleep will inform future interventions for improving sleep with potential downstream effect on obesity and other chronic disorders.
2. A cross-sectional study of patients with extreme obesity indicated that the prevalence of sleep disturbance is high in this patient population. There was a positive association between sleep disturbance factors and depressive symptoms and quality of life among these individuals. The findings emphasise the importance of adequate assessment and treatment of sleep problems in this patient population.
3. A systematic review and meta-analysis assessed the effectiveness of lifestyle modification interventions on the treatment of obstructive sleep apnoea (OSA). Lifestyle interventions such as dietary and physical activity improved OSA parameters, but were insufficient to normalise them. The findings will inform the development of future interventions for OSA, and are likely to contribute to clinical guidelines for OSA management.

Type of Work:Ph.D. thesis.
Supervisor(s):Taheri, Shahrad and Thomas, G. Neil
School/Faculty:Colleges (2008 onwards) > College of Medical & Dental Sciences
Department:School of Clinical and Experimental Medicine
Subjects:RA0421 Public health. Hygiene. Preventive Medicine
RC Internal medicine
Institution:University of Birmingham
ID Code:5425
This unpublished thesis/dissertation is copyright of the author and/or third parties. The intellectual property rights of the author or third parties in respect of this work are as defined by The Copyright Designs and Patents Act 1988 or as modified by any successor legislation. Any use made of information contained in this thesis/dissertation must be in accordance with that legislation and must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the permission of the copyright holder.
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