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Self Injury in 1p36 Deletion Syndrome

Marr, Abby (2009)
Clin.Psy.D. thesis, University of Birmingham.

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Abstract

Studies of 1p36 deletion syndrome have focused on physical characteristics with limited exploration of the behavioural phenotype. When behavioural features have been reported, self-injury and aggression are noted. This study aimed to describe these behaviours and investigate aetiology. The prevalence of self-injurious and aggressive behaviour in 1p36 deletion syndrome (n=23) were compared with three matched syndrome groups; Angelman (n=21); Cri du Chat (n=23) and Cornelia de Lange (n=23) syndromes. Carers completed questionnaires regarding self-injury, physical aggression, mood, autism spectrum disorder, hyperactivity and repetitive behaviour. Experimental functional analysis was carried out with six children. Fourteen (60.9%) participants in the 1p36 deletion syndrome group showed self injury and twelve (52.2%) showed physical aggression, with self biting found to be the most common topography of self-injury. Self-injurious behaviour was associated with overactivity and stereotyped behaviour and aggression was associated with impulsivity and repetitive behaviour. Behavioural data confirmed high levels of hand mouthing and for three participants there was evidence of attention maintained function of self injury. The findings are consistent with previous research. The implications for treatment of self-injury are discussed within the context of shaping precursor behaviours to have a communicative function prior to the development of self-injurious behaviour.

Type of Work:Clin.Psy.D. thesis.
Supervisor(s):Oliver, Christopher
School/Faculty:Colleges (2008 onwards) > College of Life & Environmental Sciences
Department:School of Psychology
Subjects:BF Psychology
Institution:University of Birmingham
ID Code:523
This unpublished thesis/dissertation is copyright of the author and/or third parties. The intellectual property rights of the author or third parties in respect of this work are as defined by The Copyright Designs and Patents Act 1988 or as modified by any successor legislation. Any use made of information contained in this thesis/dissertation must be in accordance with that legislation and must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the permission of the copyright holder.
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