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The biomechanical analysis of the hand in rheumatoid arthritis patients with MCP arthroplasty

Lester, Louise Elizabeth (2009)
M.Res. thesis, University of Birmingham.

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Abstract

Rheumatoid arthritis (RA) is a chronic inflammatory disease, causing extreme deformity, pain and swelling of joints, severely affecting quality of life. Arthroplasty has had considerable success in larger joints such as the hip. The most frequently used artificial finger joints rely on a silicone elastomer component for their flexibility. However, success of these implants has been mixed; with fracture rates for the elastomer component reported to be up to 82%. It is currently unknown why fracture of the elastomer occurs so frequently. Motion analysis was used to determine range of motion (ROM) of the metacarpophalangeal (MCP) joints in patients with rheumatoid arthritis, both without and with arthroplasty, to determine how the procedure affects motion of the joint. A 12 camera motion capture system was used to capture hand kinematic data. Preliminary experiments determined the best positions for reflective markers for measuring motion. Subjects consisted of a control population (20) and a patient population (10 without surgery and 10 with). Data were processed to give maximum, minimum and ROMs of flexion/extension and abduction/adduction at all MCPs during four movements: pinch grip, key grip, fist clench and hand spread. Results showed ROM was decreased by ageing, further by RA, and further again by replacement surgery. MCP surgery patients produced significantly lower ROMs than all other groups, suggesting the implants may not restore movement.

Type of Work:M.Res. thesis.
Supervisor(s):Hukins, David W. L. and Shepherd, Duncan E. T.
School/Faculty:Colleges (2008 onwards) > College of Engineering & Physical Sciences
Department:Department of Metallurgy & Materials and Department of Mechanical & Manufacturing Engineering
Additional Information:

The data files associated with this thesis are stored offline, and available on request

Subjects:TJ Mechanical engineering and machinery
TS Manufactures
Institution:University of Birmingham
ID Code:441
This unpublished thesis/dissertation is copyright of the author and/or third parties. The intellectual property rights of the author or third parties in respect of this work are as defined by The Copyright Designs and Patents Act 1988 or as modified by any successor legislation. Any use made of information contained in this thesis/dissertation must be in accordance with that legislation and must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the permission of the copyright holder.
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