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Perinatal factors and umbilical cord characteristics in determining handedness: results from the Belgian East Flanders prospective twin survey

Gopalakrishnan, Somasundari (2012)
M.Phil. thesis, University of Birmingham.

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Abstract

Aims: The objective was to determine if perinatal factors and umbilical cord characteristics showed any association with left-handedness in a set of twin subjects.

Subjects: Twins born from 1977 to 1991 and registered in the ongoing East Flanders Prospective Twin Survey (EFPTS) were studied.

Methods: Handedness as the outcome measure was assessed by the Strien (Preference score) questionnaire and the Bishop’s card-reaching test (Performance score). Perinatal and umbilical cord characteristics were compared in left and right-handed subjects, adjusting for twin clustering in the data. Random effects logistic modelling was used to predict the odds of being left-handed.

Findings: Out of the 15 factors tested, only 2 had statistically significant relationships with left-handedness when assessed by Strien questionnaire.

Left-handedness was less common in older fathers (odds ratio (OR) per year increase in age=0.95 (0.91-1.00) and in non-primiparous births (OR=0.68 (0.48-0.97)) Left-handedness was also less common in subjects with undefined and mixed umbilical cord windings (OR= 0.61 (0.37-1.00) when compared to clockwise windings), though the factor as a whole was not significant (p=0.13).
Bishop’s test did not confirm these findings.
Conclusion: Perinatal factors studied were not found to be significantly associated with
left-handedness.

Type of Work:M.Phil. thesis.
Supervisor(s):Powell, Judy and Skelton, John and Whetstone, Jan
School/Faculty:Colleges (2008 onwards) > College of Life & Environmental Sciences
Department:School of Public Heath, Epidemiology and Biostatistics
Subjects:RA0421 Public health. Hygiene. Preventive Medicine
Institution:University of Birmingham
ID Code:3511
This unpublished thesis/dissertation is copyright of the author and/or third parties. The intellectual property rights of the author or third parties in respect of this work are as defined by The Copyright Designs and Patents Act 1988 or as modified by any successor legislation. Any use made of information contained in this thesis/dissertation must be in accordance with that legislation and must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the permission of the copyright holder.
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