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Generalised treatment effects after rehabilitation in patients with neuropsychological deficits: the role of cognitive models.

Harris, Lara (2011)
Ph.D. thesis, University of Birmingham.

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The current thesis explored diagnosis and rehabilitation of deficits in memory and language, using a multiple neuropsychological case study design. Broadly, the work evaluated the use of cognitive theory to diagnose patients’ clinical presentations and inform rehabilitation methods, and explored how outcomes from these interventions can be used to test cognitive theory in turn. This bi-directional link was explored in two ways: Firstly, theoretically-motivated groupings of word stimuli (e.g. ‘neighbourhoods’) were used to evaluate patterns of post-therapy generalisation, testing hypothesised associations between types of word stimuli. Secondly, the work identified proposed links between cognitive functions, using rehabilitation to test the validity, and nature, of these associations. The thesis is therefore comprised of two parts: Part 1 explored ‘neighbourhood’ effects in language and how they might be used to direct generalised improvement following rehabilitation (Chapters 2, 3, 4 and 5) and Part 2 evaluated associations and dissociations of functions in the cognitive architecture, across therapeutic and experimental contexts (Chapters 6 and 7). The work demonstrated that using theoretically-driven stimuli sets in rehabilitation can maximise generalised improvements following language treatment, and detailed how rehabilitation can be harnessed to test the integrity of associations between cognitive functions in the context of multiple deficits.

Type of Work:Ph.D. thesis.
Supervisor(s):Humphreys, Glyn W. and Olson, Andrew C
School/Faculty:Colleges (2008 onwards) > College of Life & Environmental Sciences
Department:Behavioural Brain Sciences Centre, School of Psychology
Subjects:BF Psychology
HV Social pathology. Social and public welfare
P Philology. Linguistics
RB Pathology
RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Institution:University of Birmingham
ID Code:2968
This unpublished thesis/dissertation is copyright of the author and/or third parties. The intellectual property rights of the author or third parties in respect of this work are as defined by The Copyright Designs and Patents Act 1988 or as modified by any successor legislation. Any use made of information contained in this thesis/dissertation must be in accordance with that legislation and must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the permission of the copyright holder.
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