Surface active lanthanide complexes for sensing applications on silica and gold surfaces

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Khan, Suleman Manawar (2015). Surface active lanthanide complexes for sensing applications on silica and gold surfaces. University of Birmingham. Ph.D.

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Abstract

The work presented in this thesis investigates the use of new luminescent lanthanide bis-amide DTPA complexes, both in solution and bound to gold and silica surfaces. The bis-amide arms have been modified with surface attachment groups consisting of disulphides, thioacetates and silyl ethers. Both sensitising and non-sensitising bisamides arms were attached to DTPA in order to develop the best lanthanide based sensor. When these visible and NIR emitting lanthanide complexes are bound to the surface they can be used to detect various small analytesm including benzoic acid, phthalic acid, isophthalic acid, picolinic acid, dipicolinic acid, quinaldic acid, dibenzoyl methane and curcumin. The detection of analytes was performed on surfaces and in solution allowing for comparisons between the two techniques to be made. Lanthanide complexes were attached to silica microparticles and they were used for detection of analytes under flow conditions; these studies were compared to surface and solution analyte detection. The lanthanide-based silica microparticles were developed further to show the advantages of bimodal luminescent silica microparticles. The development of self-assembled monolayers of the lanthanide complexes on gold were studied using surface plasmon resonance and ellipsometry.

Type of Work:

Thesis (Doctorates > Ph.D.)

Award Type:

Doctorates > Ph.D.

Supervisor(s):